A deadly fire that began at Cuba’s main oil terminal in Matanzas has spread after a third crude tank caught fire and collapsed as firefighters struggled to fight the massive blaze.

At least one person has died and 125 are injured, with dozens of firefighters reported missing ever since lighting struck one of the facility’s eight tanks on Friday night. A second tank caught fire on Saturday, triggering several explosions at the facility, which plays a key part in Cuba’s electric system.

“The risk we had announced happened, and the blaze of the second tank compromised the third one,” said Mario Sabines, governor of the western province of Matanzas, where the facility is located.

Sabines compared the situation to an “Olympic torch” going from one tank to the next, turning each into a “caldron” and now encompassing the area covering three tanks and with flames and billowing black smoke.

Firefighters had sprayed water on the remaining tanks over the weekend to cool them and try to stop the fire from spreading. A fourth tank is threatened, but has yet to catch fire.

The governments of Mexico and Venezuela have sent special teams to help extinguish the fire, with water cannons, planes and helicopters fighting the fire from several directions, as military constructions specialists erected barriers to contain oil spills.

Local officials warned residents to use face masks or stay indoors given the billowing smoke enveloping the region that could be seen from the capital of Havana, more than 65 miles (100km) away. Officials have warned that the cloud contains sulfur dioxide, nitrogen oxide, carbon monoxide and other poisonous substances.

The majority of those injured were treated for burns and smoke inhalation, and five of them remain in critical condition. Twenty-four remain hospitalized. Over the weekend, authorities found the body of one firefighter as relatives of those still missing gathered at a hotel to await news about their loved ones.

Governor Sabines and Cuban president Miguel Díaz-Canel said it was impossible to search for the missing firefighters given the roiling temperatures.

The blaze at the Matanzas Supertanker Base in Matanzas city prompted officials to evacuate more than 4,900 people, most of them from the nearby Dubrocq neighborhood.

Jorge Piñon, director of the Latin America and Caribbean Energy Program at the University of Texas, said officials should inspect the walls of tanks that are not on fire to ensure they weren’t affected. He also warned that the government must be careful before bringing the system back online once the fire is extinguished.

“If not, there’ll be another catastrophe,” he said.

Piñon noted that the facility receives Cuban crude oil – operating an oil pipeline that crosses the center of the country – to be transferred via small tankers to the thermoelectric plants that produce electricity. It is also the unloading and transshipment center for imported crude oil, fuel oil and diesel, with Cuba producing only half of the fuel required to keep its economy afloat.

The blaze comes as Cuba struggles through a deep economic crisis and faces frequent power outages amid a sweltering summer, issues that helped unleashed unprecedented anti-government protests last year.